Description

(2,5-Difluoro-Phenyl)-Methyl-Amine is a versatile fluorinated aromatic amine building block of significant importance in modern synthetic chemistry. Its value lies in its ability to introduce both an amine functionality and a difluorophenyl moiety into target molecules, enabling the fine-tuning of physicochemical properties. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of advanced materials and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity, stability, and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Precursor: Employed in the synthesis of monomers for high-performance polymers, liquid crystals, and electronic materials.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale commercial batches.

Basic Information

Product Name	(2,5-Difluoro-Phenyl)-Methyl-Amine
CAS No.	138563-58-3
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	1-(2,5-Difluorophenyl)methanamine; 2,5-Difluorobenzylamine; (2,5-Difluorophenyl)methanamine; 2,5-Difluoro-α-toluidine; 2,5-Difluorobenzyl amine; α-Amino-2,5-difluorotoluene; Benzenemethanamine, 2,5-difluoro-; 2,5-DFBA
EINECS	Contact for details

Quality Control

Our (2,5-Difluoro-Phenyl)-Methyl-Amine is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.