Description

(3,4-Difluoro-Phenyl)-Methyl-Amine is a versatile aromatic amine derivative featuring a difluorinated phenyl ring, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, reliable intermediates for their synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology treatments.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the difluoro substitution pattern can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and electronic materials where fluorinated aromatic units are required.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and R&D Laboratories: Used in medicinal chemistry and organic synthesis research for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	(3,4-Difluoro-Phenyl)-Methyl-Amine
CAS No.	138563-54-9
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	1-(3,4-Difluorophenyl)methanamine; 3,4-Difluorobenzylamine; (3,4-Difluorobenzyl)amine; 3,4-Difluoro-α-toluidine; α-Amino-3,4-difluorotoluene; 3,4-DFBA; Benzenemethanamine, 3,4-difluoro-
EINECS	Contact for details

Quality Control

Our (3,4-Difluoro-Phenyl)-Methyl-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This amine may be hygroscopic; ensure containers are sealed tightly after use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.2 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.