Description

Trichogin A Iv CAS NO 138531-93-8 is a synthetic peptaibol, a class of linear, membrane-active peptide antibiotics characterized by a high proportion of the non-proteinogenic amino acid α-aminoisobutyric acid (Aib). This compound is valued for its potent antimicrobial and ion channel-forming properties, making it a critical tool in biophysical and biochemical research. It is primarily utilized by research institutions and pharmaceutical companies investigating novel antimicrobial agents, membrane biophysics, and peptide-based therapeutics.

Application

• Biophysical Research: Used as a model compound for studying the mechanisms of ion channel formation and pore stability in lipid bilayers.
• Antimicrobial Studies: Serves as a reference standard in assays evaluating the activity of peptaibols against bacteria, fungi, and other microorganisms.
• Membrane Protein Research: Employed to investigate peptide-lipid interactions and the perturbation of membrane integrity.
• Pharmaceutical Development: Acts as a lead compound or structural template in the design of new peptide-based antibiotics and therapeutics.
• Academic Research: Utilized in university and institutional labs for teaching and advanced research in peptide chemistry and microbiology.

Basic Information

Product Name	Trichogin A Iv
CAS No.	138531-93-8
Molecular Formula	C58H103N15O13
Molecular Weight	1206.5 g/mol
Synonyms	Trichogin A IV; Trichogin A4; Peptaibol Trichogin A Iv; Antibiotic Trichogin A Iv; [Ile11]Trichogin GA IV; 1,11-Dideoxy-1,11-diamino-3,5,7,9-tetramethylundecapeptaibolicin; Linear peptide antibiotic from Trichoderma longibrachiatum
EINECS	Contact for details

Quality Control

Our Trichogin A Iv is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to relevant quality standards suitable for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in DMSO, methanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.