Description

7-Fluoro-D-Tryptophan is a fluorinated, non-natural enantiomer of the essential amino acid tryptophan. This compound is a critical chiral building block and biochemical probe, valued for its role in modulating protein structure and function through targeted fluorination. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced peptide synthesis, metabolic pathway studies, and the development of novel radiopharmaceuticals and PET tracers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of fluorinated peptide-based drugs and bioactive molecules.
• Biochemical Research: Used as a stable isotopic or fluorinated analog in metabolic studies, enzyme mechanism investigations, and protein engineering.
• PET Tracer Development: Serves as a precursor for fluorine-18 labeled compounds used in positron emission tomography (PET) imaging.
• Peptide Synthesis: Incorporated into custom peptides to study the effects of fluorination on peptide stability, conformation, and biological activity.
• Microbiology & Nutrition Studies: Employed in research on bacterial amino acid auxotrophy and specialized microbial growth media.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in chromatographic analysis.

Basic Information

Item	Details
Product Name	7-Fluoro-D-Tryptophan
CAS No.	138514-98-4
Molecular Formula	C₁₁H₁₁FN₂O₂
Molecular Weight	222.22 g/mol
Synonyms	(R)-2-Amino-3-(7-fluoro-1H-indol-3-yl)propanoic acid; D-7-Fluorotryptophan; (R)-7-Fluorotryptophan; 7-F-D-Trp; 7-Fluoro-D-Trp; 7-FTryptophan D-isomer; 7-Fluoro-(R)-Tryptophan; 7-Fluoro-D-TRP
EINECS	Contact for details

Quality Control

Our 7-Fluoro-D-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.