Description

7-Fluoro-L-Tryptophan is a fluorinated derivative of the essential amino acid L-tryptophan, serving as a critical building block in advanced biochemical research and pharmaceutical development. This compound is valued for its role in modulating protein structure and function, enabling studies on enzyme mechanisms, receptor binding, and metabolic pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for drug discovery, proteomics, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluorinated drug candidates, particularly in oncology and neurology research.
• Biochemical Research: Used as a non-natural amino acid for protein engineering, site-specific labeling, and studying protein folding and stability.
• Proteomics & Metabolomics: Serves as a stable isotope-labeled analog or a tracer in mass spectrometry-based studies of metabolic flux and protein synthesis.
• Enzyme Inhibition Studies: Employed to investigate enzyme active sites and develop selective inhibitors due to the electronegative fluorine atom.
• Agrochemical Development: A potential intermediate in creating new fluorinated pesticides or plant growth regulators.
• Peptide Synthesis: Incorporated into custom peptides to enhance their metabolic stability, bioavailability, and binding affinity.

Basic Information

Item	Detail
Product Name	7-Fluoro-L-Tryptophan
CAS No.	138514-97-3
Molecular Formula	C11H11FN2O2
Molecular Weight	222.22 g/mol
Synonyms	(S)-2-Amino-3-(7-fluoro-1H-indol-3-yl)propanoic acid; 7-Fluoro-L-tryptophan; 7-Fluoro-L-Trp; 7-F-Trp; L-7-Fluorotryptophan; 7-Fluoro-L-α-amino-1H-indole-3-propanoic acid; 7-Fluoro-L-β-3-indolylalanine; 7-Fluorotryptophan
EINECS	Contact for details

Quality Control

Our 7-Fluoro-L-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-Isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.