Description

Vp7 Major Core Antigen, African Horsesickness Virus is a highly purified recombinant protein derived from the major core antigen of the African Horsesickness Virus (AHSV). This antigen is critical for the development of sensitive and specific diagnostic assays and research into the pathogenesis and immunology of this economically significant animal disease. It is an essential reagent for veterinary diagnostic laboratories, vaccine research and development teams, and academic institutions focused on virology and equine health.

Application

• Diagnostic Kit Development: Primary component for ELISA, immunoblot, and lateral flow assays to detect AHSV antibodies or antigens.
• Vaccine Research: Used as a reference antigen in immunogenicity studies and for evaluating vaccine candidate efficacy.
• Serological Surveillance: Key reagent for monitoring AHSV exposure and seroprevalence in equine and other susceptible animal populations.
• Antibody Production: Immunogen for generating polyclonal or monoclonal antibodies specific to the AHSV VP7 core protein.
• Basic Virology Research: Tool for studying virus structure, assembly, and host-cell interactions.
• Quality Control: Reference standard for the validation and lot-release testing of commercial diagnostic kits.

Basic Information

Product Name	Vp7 Major Core Antigen, African Horsesickness Virus
CAS No.	138413-77-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	AHSV VP7 Antigen; African Horse Sickness Virus VP7 Protein; Recombinant AHSV Core Antigen; VP7 Major Core Protein; Bluetongue Virus Group Antigen (related); Orbivirus Group Antigen; Diagnostic Grade VP7; AHSV Diagnostic Antigen
EINECS	Contact for details

Quality Control

Our Vp7 Major Core Antigen is produced under stringent quality management systems. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation by Western Blot, and functional validation in standardized immunoassays. Certificates of Analysis (COA) detailing purity, concentration, endotoxin levels, and biological activity are provided with every shipment to ensure traceability and meet the rigorous standards of diagnostic and research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Identification (Western Blot)	Reacts with specific anti-AHSV/VP7 antisera
Purity (SDS-PAGE)	≥ 90%
Protein Concentration	As per COA (typically 0.5 - 1.0 mg/mL)
Endotoxin Level	< 1.0 EU/µg (by LAL test)
Biological Activity (ELISA)	Positive reactivity in standardized assay
Buffer Composition	PBS, pH 7.4 (or as specified on COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.