Description

Amylin (8-37) (Rat) is a specific peptide fragment derived from the rat amylin hormone, with the CAS registry number 138398-61-5. This compound is a valuable research-grade antagonist used to study the physiological role and signaling pathways of amylin, particularly in metabolic processes. It is essential for researchers and pharmaceutical developers in the fields of endocrinology, diabetes research, and metabolic disorder studies who require high-purity biochemical tools.

Application

• Biomedical Research: Used as a selective antagonist in receptor binding assays and signal transduction studies to investigate amylin's function.
• Metabolic Pathway Analysis: Critical for in vitro and in vivo studies exploring the role of amylin in glucose metabolism, insulin secretion, and satiety.
• Drug Discovery & Development: Serves as a reference standard and pharmacological tool in the screening and development of novel therapeutics for diabetes and obesity.
• Academic & Institutional Studies: Employed in university and research institute laboratories for fundamental studies on peptide hormones and their fragments.
• Biochemical Reagent: Acts as a key reagent in the development and validation of diagnostic assays related to metabolic health.

Basic Information

Product Name	Amylin (8-37) (Rat)
CAS No.	138398-61-5
Molecular Formula	C144H238N44O43S2
Molecular Weight	3249.8 g/mol
Synonyms	Rat Amylin (8-37); Amylin Fragment 8-37, rat; IAPP (8-37) (rat); Islet Amyloid Polypeptide (8-37), rat; rAmylin(8-37); rIAPP(8-37); [Rat] Amylin 8-37
EINECS	Contact for details

Quality Control

Our Amylin (8-37) (Rat) is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical results are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.