Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl Phe-Pro-Oh is a specialized Fmoc-protected dipeptide building block, essential for solid-phase peptide synthesis (SPPS). This compound provides critical control over the coupling sequence, enabling the precise construction of complex peptides and peptidomimetics. It is primarily required by research institutions and pharmaceutical companies engaged in the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential addition of phenylalanine and proline residues using Fmoc chemistry.
• Therapeutic Peptide Research: Used in the R&D of novel peptide-based drugs targeting metabolic disorders, oncology, and cardiovascular diseases.
• Bioconjugation & Probe Development: Serves as a building block for creating labeled peptides used in imaging, diagnostics, and targeted drug delivery systems.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening and drug discovery.
• Enzyme Substrate & Inhibitor Studies: Useful for synthesizing specific peptide sequences to study protease activity and inhibition.
• Academic & Industrial Research: A fundamental reagent for biochemical research in universities, CROs (Contract Research Organizations), and biotech companies.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl Phe-Pro-Oh
CAS No.	138372-76-6
Molecular Formula	C30H30N2O5
Molecular Weight	498.57 g/mol
Synonyms	Fmoc-Phe-Pro-OH; Fmoc-L-Phenylalanyl-L-proline; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-L-proline; N-α-Fmoc-L-phenylalanyl-L-proline; Fmoc-Phenylalanine-Proline; Fmoc-Phe-Pro; (9-Fluorenylmethoxycarbonyl)-Phe-Pro; L-Phenylalanyl-L-proline N-[(9H-fluoren-9-ylmethoxy)carbonyl] derivative
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl Phe-Pro-Oh is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), chiral purity, and identification data. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-L isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.