Description

Microcystin-Wr is a potent cyclic heptapeptide hepatotoxin produced by certain freshwater cyanobacteria. This compound is of critical importance for environmental monitoring, toxicological research, and the development of detection methods for cyanobacterial blooms. It is primarily required by analytical laboratories, research institutions, and environmental agencies focused on water safety and public health.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the precise quantification of microcystins in water samples via HPLC, LC-MS/MS, or ELISA.
• Toxicological Research: Essential for studying the mechanisms of hepatotoxicity, including protein phosphatase inhibition and oxidative stress, in both in vitro and in vivo models.
• Method Development & Validation: Serves as a critical component in developing, calibrating, and validating new analytical methods for cyanotoxin detection.
• Environmental Monitoring: Employed in quality control and assurance programs for laboratories monitoring drinking water reservoirs, recreational waters, and algal blooms.
• Antibody & Assay Production: Used as an antigen for the production of specific antibodies and the development of immunoassay kits for rapid field testing.
• Regulatory Compliance Testing: Supports testing to comply with national and international water quality guidelines regarding cyanotoxin limits.

Basic Information

Product Name	Microcystin-Wr
CAS No.	138234-58-9
Molecular Formula	C49H74N10O12
Molecular Weight	995.2 g/mol
Synonyms	Microcystin WR; [D-Asp3, Dha7]Microcystin-LR; Cyanoginosin WR; MC-WR; Microcystin variant WR; (all-*S*)-3-Amino-12-[(2*S*)-2-[[(2*S*,4*E*)-5-[[(2*S*)-1-[[(4*R*)-4-[[(2*S*)-5-Amino-1-[[(2*S*,3*S*)-1-[[(2*S*)-4-[[(2*S*)-1-[[(2*S*)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-hydroxy-1-oxobutan-2-yl]amino]-5-methyl-1-oxohex-4-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaazacyclohexadec-15-yl]acetic acid
EINECS	Contact for details

Quality Control

Our Microcystin-Wr is produced and handled under strict quality protocols suitable for research and analytical applications. Each batch undergoes rigorous identity confirmation and purity analysis via advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, identity (HPLC, MS), and other critical parameters is provided to ensure traceability and support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term stability, store under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 5.0 %
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.