Description

Deltorphin Ii, Ile(5,6)- CAS NO 138166-93-5 is a synthetic, highly selective delta opioid receptor (DOR) agonist peptide. This compound is a critical research tool for investigating the physiological and pharmacological roles of the delta opioid receptor system in pain modulation, neurological disorders, and addiction. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuropharmacology and novel analgesic development.

Application

• Neuroscience Research: Used as a selective ligand to study delta opioid receptor (DOR) signaling pathways, distribution, and function in the central and peripheral nervous systems.
• Analgesic Drug Discovery: Serves as a reference compound and pharmacological tool in the development of novel, non-addictive pain therapeutics targeting the delta opioid receptor.
• In Vitro & In Vivo Studies: Employed in receptor binding assays, functional activity tests (e.g., cAMP inhibition), and animal models to evaluate antinociceptive effects and side-effect profiles.
• Biochemical Mechanism Studies: Facilitates research into receptor internalization, G-protein coupling, and downstream effector mechanisms specific to DOR activation.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in peptide synthesis and pharmacological testing.

Basic Information

Product Name	Deltorphin Ii, Ile(5,6)-
CAS No.	138166-93-5
Molecular Formula	C45H62N10O11
Molecular Weight	919.04 g/mol
Synonyms	Deltorphin II; [Ile5,6]Deltorphin II; Deltorphin C; H-Tyr-D-Ala-Phe-Glu-Ile-Ile-Gly-NH2; Tyr-D-Ala-Phe-Glu-Ile-Ile-Gly-amide; δ-opioid receptor agonist peptide; DOR agonist
EINECS	Contact for details

Quality Control

Our Deltorphin Ii, Ile(5,6)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.