Description

1,12-Dimethylspermine CAS NO 137946-03-3 is a synthetic polyamine derivative of the naturally occurring spermine molecule. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a modulator of cellular polyamine metabolism and function. It serves as a critical intermediate and research tool for scientists in the fields of oncology, cell biology, and drug discovery, where precise control of polyamine pathways is essential.

Application

• Biochemical Research: Used as a reference standard and probe to study polyamine transport, biosynthesis, and catabolism in cellular systems.
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the synthesis of novel therapeutic agents targeting cancer, parasitic diseases, and neurological disorders.
• Enzyme Inhibition Studies: Acts as a substrate or inhibitor for enzymes like spermine/spermidine acetyltransferase and other polyamine-metabolizing enzymes.
• Cell Culture & Physiology: Employed to investigate the effects of polyamine analogs on cell growth, differentiation, and apoptosis.
• Academic Research: Utilized in universities and research institutes for fundamental studies on polyamine biology and its implications in aging and disease.

Basic Information

Product Name	1,12-Dimethylspermine
CAS No.	137946-03-3
Molecular Formula	C8H22N4
Molecular Weight	174.29 g/mol
Synonyms	N1,N12-Dimethylspermine; N1,N12-Dimethylspermine; 1,12-Bis(methylamino)-4,9-diazadodecane; Tetramethylenediamine, N,N'-bis(3-aminopropyl)-, N,N'-dimethyl-; Polyamine analog; Spermine derivative
EINECS	Contact for details

Quality Control

Our 1,12-Dimethylspermine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.