Description

Neuromedin U 9 is a synthetic peptide fragment of the larger neuromedin U hormone, a potent regulator of smooth muscle contraction and energy homeostasis. This high-purity reference standard is critical for ensuring the accuracy and reproducibility of bioanalytical research and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroendocrine studies, metabolic disorder research, and the development of novel therapeutic agents targeting the NMU receptor system.

Application

• Biomedical Research: As a reference standard in assays studying the biological functions of neuromedin U, including its effects on smooth muscle contraction, food intake, and energy expenditure.
• Drug Discovery & Development: Used in high-throughput screening (HTS) and binding assays to identify and characterize new agonists or antagonists for the NMU receptors (NMUR1 and NMUR2).
• Analytical Method Development: Serves as a critical calibrant and system suitability standard for developing and validating analytical methods, particularly in Liquid Chromatography-Mass Spectrometry (LC-MS/MS).
• Peptide Chemistry Studies: Employed in structure-activity relationship (SAR) studies to understand the pharmacophore of neuromedin U and design peptide analogs with modified potency or selectivity.
• Quality Control in Peptide Synthesis: Acts as a benchmark for purity and identity in the commercial production of longer neuromedin U peptide sequences or related analogs.

Basic Information

Product Name	Neuromedin U 9
CAS No.	137811-42-8
Molecular Formula	C50H78N16O13S
Molecular Weight	1119.3 g/mol
Synonyms	Neuromedin U (25-33); H-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; NMU-9; NMU (25-33); Neuromedin U-9; Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-amide; Neuromedin U fragment 25-33; Porcine Neuromedin U-9
EINECS	Contact for details

Quality Control

Every batch of Neuromedin U 9 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and pre-clinical applications. A comprehensive Certificate of Analysis (COA), detailing results for purity (HPLC), peptide content, and identity confirmation (MS), is provided with each shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.