Description

Msh (5-10), Cyclic is a synthetic peptide fragment derived from the melanocyte-stimulating hormone (MSH) sequence. This compound is of significant interest in biochemical and pharmaceutical research due to its role in studying melanocortin receptor interactions and signaling pathways. It serves as a critical intermediate and reference standard for researchers in endocrinology, dermatology, and drug discovery.

Application

• Biochemical Research: Used as a reference standard and tool compound for studying melanocortin receptor (MCR) subtypes, particularly MC1R.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of novel peptide-based therapeutics targeting skin pigmentation disorders, inflammation, and appetite regulation.
• Academic Studies: Employed in university and institutional labs to investigate the structure-activity relationships (SAR) of MSH peptide analogs.
• Diagnostic Reagent Manufacturing: Utilized in the production of high-sensitivity assay kits and reagents for hormonal research.
• Cosmeceutical Research: Investigated for potential applications in advanced skincare formulations targeting melanogenesis.

Basic Information

Product Name	Msh (5-10), Cyclic
CAS No.	137668-62-3
Molecular Formula	C34H50N10O9S
Molecular Weight	774.89 g/mol
Synonyms	Cyclo(acetyl-c[Asp-His-D-Phe-Arg-Trp-Lys]); Ac-c[CH2CO-His-D-Phe-Arg-Trp-Lys]-NH2; Melanocyte-Stimulating Hormone (5-10) cyclic analog; MSH (5-10) cyclic peptide; SHU 9119 (common research alias); Ac-cyclo[Asp5, D-Phe7, Lys10] α-MSH(5-10)-NH2; MC1R/MC3R antagonist peptide
EINECS	Contact for details

Quality Control

Our Msh (5-10), Cyclic is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.