Description

Parathyroid Hormone (68-84) is a bioactive peptide fragment corresponding to the C-terminal region of the full-length parathyroid hormone. This compound is a critical research tool for studying calcium and phosphate metabolism, bone biology, and the pathophysiology of parathyroid disorders. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on endocrine and metabolic diseases.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of PTH receptor signaling, bone resorption, and mineral ion homeostasis.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the development of PTH-based therapeutics for osteoporosis and hypoparathyroidism.
• Diagnostic Assays: Employed in the calibration and validation of immunoassays (e.g., ELISA, RIA) designed to detect and quantify PTH or related fragments in clinical samples.
• Cell Biology Studies: Applied in *in vitro* cell culture models to investigate the effects of PTH on osteoblast and osteoclast activity.
• Structure-Activity Relationship (SAR) Studies: Essential for mapping bioactive regions of the parathyroid hormone and designing peptide analogs with modified potency or selectivity.
• Quality Control: Acts as a system suitability standard in the analytical testing of PTH-related pharmaceutical products.

Basic Information

Product Name	Parathyroid Hormone (68-84)
CAS No.	137593-42-1
Molecular Formula	C92H147N29O26S
Molecular Weight	2095.4 g/mol
Synonyms	PTH (68-84); Parathyroid Hormone Fragment 68-84; hPTH (68-84); Human Parathyroid Hormone (68-84); C-Terminal Parathyroid Hormone Fragment; CAS 137593-42-1; PTH C-terminal peptide
EINECS	Contact for details

Quality Control

Our Parathyroid Hormone (68-84) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, peptide content, and analytical results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.