Description

L-Asp-L-Lys-L-Phe-L-Val-Gly-n-Methyl-L-Leu-L-Nle-Nh2 is a synthetic peptide sequence of significant interest in advanced pharmaceutical research and development. This compound matters for its potential role as a key intermediate or active pharmaceutical ingredient (API) in the creation of novel therapeutic agents, particularly in areas requiring specific receptor targeting. Pharmaceutical companies, biotechnology research firms, and contract development and manufacturing organizations (CDMOs) engaged in peptide-based drug discovery are the primary industrial users of this material.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex peptide-based Active Pharmaceutical Ingredients (APIs).
• Drug Discovery & Development: Used in preclinical research for screening biological activity, studying structure-activity relationships (SAR), and optimizing lead compounds.
• Biochemical Research: Employed as a tool compound in academic and industrial laboratories to investigate specific peptide-protein interactions and signaling pathways.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in peptide manufacturing and analysis.
• Peptide Library Synthesis: Incorporated into combinatorial libraries for high-throughput screening to identify new drug candidates with desired biological properties.

Basic Information

Product Name	L-Asp-L-Lys-L-Phe-L-Val-Gly-n-Methyl-L-Leu-L-Nle-Nh2
CAS No.	137565-28-7
Molecular Formula	C41H68N10O10
Molecular Weight	861.04 g/mol
Synonyms	Asp-Lys-Phe-Val-Gly-N-Me-Leu-Nle-NH2; H-Asp-Lys-Phe-Val-Gly-N-Me-Leu-Nle-NH2; Aspartyl-Lysyl-Phenylalanyl-Valyl-Glycyl-N-Methyl-Leucyl-Norleucinamide; DKPFVG-N-Me-L-Nle-NH2; Peptide Sequence 137565-28-7; Norleucine-containing heptapeptide amide; N-Methyl-leucine peptide derivative
EINECS	Contact for details

Quality Control

Our L-Asp-L-Lys-L-Phe-L-Val-Gly-n-Methyl-L-Leu-L-Nle-Nh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide full traceability and a Certificate of Analysis (COA) with each shipment, detailing all critical quality attributes. Production can be aligned with cGMP guidelines for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For extended storage under inert atmosphere, consider.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.