Description

Pyrimidine, 2-[4-(2-Pyrazinyl)-1-Piperazinyl]- is a heterocyclic organic compound featuring a pyrimidine core linked to a piperazine ring bearing a pyrazinyl substituent. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile building block in medicinal chemistry research. It is primarily sought by pharmaceutical R&D and fine chemical synthesis sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Reagent: May serve as a reference standard or a ligand in biochemical assays and pharmacological studies.
• Organic Synthesis: A versatile precursor for synthesizing more complex heterocyclic compounds due to its reactive nitrogen sites.
• Agrochemical Research: Potential intermediate in the development of new pesticides or herbicides, leveraging its heterocyclic structure.

Basic Information

Product Name	Pyrimidine, 2-[4-(2-Pyrazinyl)-1-Piperazinyl]-
CAS No.	137448-39-6
Molecular Formula	C12H14N6
Molecular Weight	242.28 g/mol
Synonyms	2-[4-(Pyrazin-2-yl)piperazin-1-yl]pyrimidine; 2-(4-Pyrazin-2-ylpiperazin-1-yl)pyrimidine; 2-(4-(2-Pyrazinyl)-1-piperazinyl)pyrimidine; 1-(Pyrimidin-2-yl)-4-(pyrazin-2-yl)piperazine; 2-(4-Pyrazin-2-yl-piperazin-1-yl)-pyrimidine; 2-Piperazinylpyrimidine derivative; CAS 137448-39-6
EINECS	Contact for details

Quality Control

Our production of Pyrimidine, 2-[4-(2-Pyrazinyl)-1-Piperazinyl]- adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.