Description

2,4(1H,3H)-Pyrimidinedione,5-Fluoro-3-(Hydroxymethyl)-(9Ci) is a high-purity fluorinated pyrimidine derivative, a key building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its unique structural features that enable targeted molecular modifications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated nucleoside analogs and antiviral/anticancer drug candidates.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and stability.
• Biochemical Research: Serves as a modified base analog in oligonucleotide synthesis for probing nucleic acid structure and function.
• Fine Chemical Synthesis: Employed as a specialized building block for creating complex molecules in material science and chemical biology.
• Process Development: Utilized in route scouting and optimization for the scalable production of fluorinated target molecules.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione,5-Fluoro-3-(Hydroxymethyl)-(9Ci)
CAS No.	137442-18-3
Molecular Formula	C5H5FN2O3
Molecular Weight	160.10 g/mol
Synonyms	5-Fluoro-3-(hydroxymethyl)uracil; 5-Fluoro-3-(hydroxymethyl)-2,4(1H,3H)-pyrimidinedione; 3-(Hydroxymethyl)-5-fluorouracil; 5-Fluoro-3-hydroxymethyluracil; 5-Fluoro-1H,3H-pyrimidine-2,4-dione-3-methanol; 5-Fluoro-3-(hydroxymethyl)-1H-pyrimidine-2,4-dione
EINECS	Contact for details

Quality Control

Our 2,4(1H,3H)-Pyrimidinedione,5-Fluoro-3-(Hydroxymethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.