Description

Tyrosyl-Glycyl-Prolyl-Glycyl-Phenylalanyl-Proline is a synthetic hexapeptide sequence of significant interest in biochemical and pharmaceutical research. This compound is valued for its role as a model substrate and intermediate in the study of enzymatic processes, particularly those involving collagen metabolism and peptide-based drug discovery. It serves as a critical building block for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced life science sectors who require high-purity, well-characterized peptide intermediates.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic assays to study protease activity, particularly collagenases and other matrix metalloproteinases (MMPs).
• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel peptide-based therapeutics and diagnostic agents.
• Cosmeceutical Development: Investigated for potential applications in anti-aging and skin repair formulations due to its collagen-like sequence.
• Academic Studies: Employed in university and institutional labs for fundamental research on peptide structure, stability, and bioactivity.
• Process Development: Utilized in scaling up peptide synthesis protocols and optimizing purification methodologies within process chemistry.

Basic Information

Product Name	Tyrosyl-Glycyl-Prolyl-Glycyl-Phenylalanyl-Proline
CAS No.	137372-38-4
Molecular Formula	C37H47N7O9
Molecular Weight	733.82 g/mol
Synonyms	YGPGFP; Tyr-Gly-Pro-Gly-Phe-Pro; Hexapeptide YGPGFP; L-Tyrosyl-glycyl-L-prolyl-glycyl-L-phenylalanyl-L-proline; Collagenase Substrate Peptide; MMP Substrate; Peptide Sequence 1102
EINECS	Contact for details

Quality Control

Our Tyrosyl-Glycyl-Prolyl-Glycyl-Phenylalanyl-Proline is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all relevant specifications to ensure the material meets your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with desiccant after each use to maintain purity and prevent degradation. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.