Description

Tyrosyl-Glycyl-Prolyl-Leucyl-Phenylalanyl-Proline is a synthetic hexapeptide with the sequence Tyr-Gly-Pro-Leu-Phe-Pro. This compound is a valuable research-grade biochemical tool, primarily utilized in the study of peptide structure, function, and interactions. It serves as a critical intermediate or reference standard in pharmaceutical research, biochemistry, and proteomics. Industries requiring high-purity peptide building blocks for drug discovery and diagnostic development are the primary end-users of this material.

Application

• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis of more complex peptide-based drug candidates and therapeutic agents.
• Biochemical Research: Serves as a model substrate or inhibitor in enzymatic studies, receptor binding assays, and structure-activity relationship (SAR) investigations.
• Proteomics & Peptide Chemistry: Acts as a reference standard for mass spectrometry calibration and in the development of analytical methods for peptide quantification.
• Academic Research: Employed in university and institutional labs for fundamental studies on peptide folding, stability, and bioactivity.
• Diagnostic Reagent Development: Potential use as a component in the development of immunoassays or biosensors targeting specific peptide sequences.

Basic Information

Product Name	Tyrosyl-Glycyl-Prolyl-Leucyl-Phenylalanyl-Proline
CAS No.	137372-36-2
Molecular Formula	C41H55N7O9
Molecular Weight	789.93 g/mol
Synonyms	Tyr-Gly-Pro-Leu-Phe-Pro; YGPLFP; Hexapeptide YGPLFP; L-Tyrosylglycyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline; Tyrosylglycylprolylleucylphenylalanylproline; H-Tyr-Gly-Pro-Leu-Phe-Pro-OH; TFA salt of YGPLFP (common salt form)
EINECS	Contact for details

Quality Control

Our Tyrosyl-Glycyl-Prolyl-Leucyl-Phenylalanyl-Proline is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Ratio within ±10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.