Description

Ac-Thr-Leu-Asn-Phe-Oh is a synthetic pentapeptide derivative featuring an acetylated N-terminus and a free C-terminal carboxylic acid. This compound is a valuable building block and research tool in peptide chemistry and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications ranging from biochemical studies to the synthesis of more complex peptide-based molecules.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel therapeutic peptides.
• Biochemical Assays: Used as a substrate or inhibitor in enzymatic studies to investigate protease activity and specificity.
• Peptide Library Construction: Acts as a building block in combinatorial chemistry for creating diverse peptide libraries for drug discovery screening.
• Structure-Activity Relationship (SAR) Studies: Employed to analyze how specific amino acid sequences influence biological activity and peptide stability.
• Academic Research: Utilized in university and institutional labs for fundamental research in biochemistry, molecular biology, and medicinal chemistry.
• Custom Peptide Synthesis: Provides a defined sequence fragment for the custom synthesis of longer, more complex peptide chains for clients.

Basic Information

Product Name	Ac-Thr-Leu-Asn-Phe-Oh
CAS No.	137372-00-0
Molecular Formula	C28H42N6O9
Molecular Weight	606.67 g/mol
Synonyms	Acetyl-Threonyl-Leucyl-Asparaginyl-Phenylalanine; Ac-T-L-N-F-OH; N-Acetyl-Thr-Leu-Asn-Phe; Acetyl-Thr-Leu-Asn-Phe; Ac-TLNFP-OH; Pentapeptide Ac-TLNFP; N-Acetyl-L-threonyl-L-leucyl-L-asparaginyl-L-phenylalanine; Ac-Thr-Leu-Asn-Phe
EINECS	Contact for details

Quality Control

Every batch of Ac-Thr-Leu-Asn-Phe-Oh is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.