Description

Epidermal Growth Factor Receptor Fragmen CAS NO 137348-21-1 is a high-purity synthetic peptide fragment derived from the Epidermal Growth Factor Receptor (EGFR), a critical transmembrane protein involved in cellular signaling pathways. This fragment is essential for biochemical research, serving as a key reagent in the study of tyrosine kinase activity, receptor-ligand interactions, and downstream signal transduction mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on oncology, cell biology, and targeted therapeutic discovery.

Application

• Biochemical Research & Assay Development: Used as a standard or substrate in enzymatic assays to study EGFR tyrosine kinase activity and inhibition.
• Pharmaceutical R&D: Serves as a critical tool for screening and characterizing potential EGFR-targeted drug candidates, including tyrosine kinase inhibitors (TKIs).
• Antibody Production & Characterization: Acts as an immunogen or antigen for the generation and validation of anti-EGFR antibodies in diagnostic and therapeutic applications.
• Cell Signaling Studies: Employed in vitro to investigate the structure-function relationship of EGFR and its role in proliferation and apoptosis pathways.
• Diagnostic Kit Development: Utilized as a calibrated reference material in the development of ELISA and other immunoassays for EGFR detection.
• Academic & Institutional Research: Provides a defined peptide fragment for fundamental research in cancer biology, molecular biology, and signal transduction.

Basic Information

Product Name	Epidermal Growth Factor Receptor Fragmen
CAS No.	137348-21-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	EGFR Fragment; Epidermal Growth Factor Receptor Peptide Fragment; EGFR Peptide; erbB-1 Fragment; HER1 Fragment; Tyrosine-protein kinase erbB-1 fragment; Receptor tyrosine-protein kinase erbB-1 fragment; CAS 137348-21-1
EINECS	Contact for details

Quality Control

Our Epidermal Growth Factor Receptor Fragmen is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in aqueous buffers or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.