Description

D-Alanine-1-13C is a stable isotope-labeled analog of the essential amino acid D-alanine, specifically enriched with carbon-13 at the C-1 position (CAS NO 137248-51-2). This high-purity labeled compound is critical for advanced research requiring precise metabolic and structural analysis. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications such as tracer studies, NMR spectroscopy, and mass spectrometry.

Application

• Metabolic Pathway Tracer Studies: Used as a stable isotope tracer to investigate amino acid metabolism, protein synthesis, and bacterial cell wall biosynthesis in research.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Serves as an essential internal standard or probe for structural elucidation and dynamic studies in complex biological systems.
• Mass Spectrometry (MS) & LC-MS/MS: Employed as a labeled internal standard for the accurate quantification of alanine and related metabolites in bioanalytical methods.
• Pharmaceutical Research & Development: Facilitates drug metabolism and pharmacokinetics (DMPK) studies for new therapeutic agents.
• Microbiological Research: Used in studies of bacterial physiology, particularly concerning D-alanine's role in peptidoglycan synthesis for cell wall formation.
• Biochemical Reagent: Acts as a high-purity substrate or building block for enzymatic assays and the synthesis of more complex labeled compounds.

Basic Information

Product Name	D-Alanine-1-13C
CAS No.	137248-51-2
Molecular Formula	C213CH7NO2 or C3H7NO2 (with 13C at C-1)
Molecular Weight	90.09 g/mol (theoretical average for 13C1 labeled)
Synonyms	(R)-2-Aminopropionic acid-1-13C; (R)-Alanine-1-13C; D-α-Alanine-1-13C; (2R)-2-Aminopropanoic acid-1-13C; D-Ala-1-13C; (R)-(+)-Alanine-1-13C; D-2-Aminopropionic acid-1-13C; Stable Isotope Labeled D-Alanine
EINECS	Contact for details

Quality Control

Our D-Alanine-1-13C is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (atom % 13C), chemical purity (by HPLC), chiral purity, and residual solvent content. We adhere to relevant industry standards for high-purity biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (atom % 13C)	≥ 99%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.