Description

Fibrinogen-Binding Peptide CAS NO 137235-80-4 is a synthetic, biologically active peptide sequence designed to specifically target and bind to fibrinogen, a key glycoprotein in the blood coagulation cascade. This targeted interaction makes it a critical research tool and a promising candidate for developing advanced hemostatic agents and diagnostic platforms. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical, and biomedical device industries for applications ranging from fundamental biochemical studies to the creation of novel therapeutic and diagnostic products.

Application

• Biomedical Research: Used as a specific probe to study fibrinogen structure, function, and its role in thrombosis, hemostasis, and inflammatory processes.
• Hemostatic Agent Development: Serves as a key component in the design of next-generation topical hemostats and sealants to control bleeding during surgery or trauma.
• Diagnostic Assays: Incorporated into immunoassays and biosensors for the specific detection and quantification of fibrinogen or fibrin degradation products in clinical samples.
• Drug Delivery Systems: Functionalized onto nanoparticle or polymer surfaces to create targeted delivery vehicles for thrombolytic or anti-thrombotic drugs.
• Biomaterial Coating: Used to modify the surface of implants, stents, or wound dressings to improve biocompatibility and control the local coagulation response.
• Antithrombotic Therapy Research: Investigated as a potential lead compound or targeting moiety for developing novel antithrombotic and anticoagulant therapeutics.

Basic Information

Product Name	Fibrinogen-Binding Peptide
CAS No.	137235-80-4
Molecular Formula	C34H59N11O12
Molecular Weight	789.9 g/mol
Synonyms	Fibrinogen Binding Peptide; GPRP Peptide; Gly-Pro-Arg-Pro; H-Gly-Pro-Arg-Pro-OH; GPRP; Fibrinogen tetrapeptide; Platelet aggregation inhibitor peptide (GPRP); Fibrin polymerization inhibitor
EINECS	Contact for details

Quality Control

Our Fibrinogen-Binding Peptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis to meet specific purity requirements (e.g., >95%, >98%) is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.