Description

Spinorphin is a synthetic hexapeptide with potent biological activity, functioning as a selective inhibitor of the enzyme leukotriene A4 hydrolase (LTA4H). This compound is a critical research tool for studying inflammatory pathways and neuroimmune interactions, offering significant value in the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on inflammation, pain management, and central nervous system disorders.

Application

• Biomedical Research: A key reagent for investigating the role of leukotriene B4 (LTB4) and aminopeptidase activity in inflammatory and neuropathic pain models.
• Drug Discovery & Development: Serves as a reference standard and lead compound for designing new anti-inflammatory and analgesic pharmaceuticals targeting the LTA4H enzyme.
• Neuroscience Studies: Used to explore the modulation of opioid peptide metabolism and its effects on pain signaling within the central nervous system.
• In Vitro & In Vivo Assays: Employed in enzymatic inhibition assays and animal studies to validate target engagement and efficacy of potential drug candidates.
• Biochemical Pathway Analysis: Essential for dissecting complex biochemical cascades involving eicosanoids and their impact on immune cell function.

Basic Information

Product Name	Spinorphin
CAS No.	137201-62-8
Molecular Formula	C34H52N10O8
Molecular Weight	728.85 g/mol
Synonyms	LVVYPWT; Leu-Val-Val-Tyr-Pro-Trp-Thr; Spinorphin (bovine); LVV-Hemorphin-7; Spinorphin, bovine; L-Valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-threonine; EC 3.4.-.- inhibitor
EINECS	Contact for details

Quality Control

Our Spinorphin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for peptide synthesis, and custom purity grades, including research and pharmaceutical development grades, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥95%
Assay (HPLC)	≥98.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Meets ICH guidelines
Peptide Content	≥80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.