Description

2-Pyrimidinamine, 4-Methoxy-6-(Trifluoromethoxy)- (9Ci) is a specialized pyrimidine derivative, a high-value chemical intermediate characterized by its unique trifluoromethoxy and methoxy substituents. This compound matters for its role in facilitating complex molecular synthesis, offering a precise structural motif that is difficult to replicate with simpler chemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, where its specific substitution pattern is critical for biological activity and patentability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the stability imparted by the fluorine atoms.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the development of specialty chemicals and advanced materials requiring specific fluorine-containing heterocycles.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	2-Pyrimidinamine, 4-Methoxy-6-(Trifluoromethoxy)- (9Ci)
CAS No.	137161-25-2
Molecular Formula	C6H6F3N3O2
Molecular Weight	209.13 g/mol
Synonyms	4-Methoxy-6-(trifluoromethoxy)pyrimidin-2-amine; 6-(Trifluoromethoxy)-4-methoxypyrimidin-2-amine; 2-Amino-4-methoxy-6-(trifluoromethoxy)pyrimidine; 4-Methoxy-6-trifluoromethoxypyrimidin-2-ylamine; 137161-25-2; SCHEMBL2184247; DTXSID60672939; AKOS025310923
EINECS	Contact for details

Quality Control

Every batch of 2-Pyrimidinamine, 4-Methoxy-6-(Trifluoromethoxy)- is produced and tested under a strict quality management system. We offer material suitable for research and development purposes, with typical purity levels exceeding 95% (HPLC). Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. For projects requiring material under cGMP guidelines or with custom specifications, please contact our technical sales team to discuss your requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; ensure it is stored separately from such materials. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.