Description

Vimentin (1-96) CAS NO 137085-30-4 is a high-purity synthetic peptide fragment corresponding to the N-terminal region of the human vimentin protein. This compound serves as a critical research tool for studying intermediate filament structure, cell signaling, and biomarker discovery. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in cancer research, cellular biology, and diagnostic assay development.

Application

• Biomarker Research & Validation: Used as a standard or antigen in studies investigating vimentin as a biomarker for epithelial-mesenchymal transition (EMT), cancer metastasis, and fibrosis.
• Antibody Production & Characterization: Serves as a key immunogen for generating and screening monoclonal or polyclonal antibodies specific to the vimentin protein.
• Diagnostic Assay Development: Employed in the development and calibration of immunoassays (ELISA, Western Blot) for the detection of vimentin or anti-vimentin antibodies in clinical samples.
• Cell Biology & Signal Transduction Studies: Used in in vitro experiments to investigate the role of vimentin fragments in cellular processes, cytoskeletal dynamics, and intracellular signaling pathways.
• Pharmaceutical Target Research: Acts as a tool compound in drug discovery programs targeting vimentin for therapeutic interventions in cancer and inflammatory diseases.
• Quality Control Reference Standard: Provides a defined peptide standard for the quality control of related biological reagents and assay kits.

Basic Information

Product Name	Vimentin (1-96)
CAS No.	137085-30-4
Molecular Formula	C453H738N136O139S2
Molecular Weight	10437.1 g/mol
Synonyms	Human Vimentin (1-96); Vimentin Fragment 1-96; VIM (1-96); Vimentin N-terminal peptide; Recombinant Vimentin Peptide; Vimentin Antigen; EMT Marker Peptide; Intermediate Filament Protein Fragment; Cytoskeletal Peptide
EINECS	Contact for details

Quality Control

Our Vimentin (1-96) is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation. We provide full traceability and a Certificate of Analysis (COA) with each shipment, detailing purity, peptide content, and analytical data. Production adheres to general quality system principles suitable for research-grade biologics.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. Aliquot into working solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Solubility	Soluble in water or appropriate aqueous buffers
Endotoxin Level	< 1.0 EU/µg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.