Description

7-(4'-(2-Nitroimidazole-1-Yl)Butyl)Theophylline is a specialized heterocyclic organic compound that serves as a key intermediate in advanced pharmaceutical research and development. This molecule is particularly significant for its structural features, combining a theophylline moiety with a nitroimidazole group via a butyl linker, which is of high interest in the design of novel bioactive agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of potential therapeutic compounds, especially in areas targeting hypoxia or requiring specific bioreductive activation.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those designed for targeting hypoxic conditions within tumors.
• Biochemical Research: Used as a reference standard or probe in studies investigating hypoxia markers and bioreductive drug mechanisms.
• Radiopharmaceutical Precursor: Potential use in the development of diagnostic imaging agents designed to bind to hypoxic tissues.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	7-(4'-(2-Nitroimidazole-1-Yl)Butyl)Theophylline
CAS No.	137046-51-6
Molecular Formula	C14H17N7O4
Molecular Weight	347.33 g/mol
Synonyms	1-Butyl-3-(7-theophyllinyl)propyl-2-nitroimidazole; 7-[4-(2-Nitro-1H-imidazol-1-yl)butyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 1,3-Dimethyl-7-[4-(2-nitroimidazol-1-yl)butyl]purine-2,6-dione; Theophylline, 7-[4-(2-nitro-1H-imidazol-1-yl)butyl]-; SR-4554 (Research Code); Hypoxia Marker Intermediate; Nitroimidazole-Theophylline Conjugate
EINECS	Contact for details

Quality Control

Our 7-(4'-(2-Nitroimidazole-1-Yl)Butyl)Theophylline is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable for pharmaceutical intermediates, and our analytical methods are validated to meet the stringent requirements of the research and development sector.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.