Description

N'-(1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethyl)-n-(3-(3-Trifluoromethyl)Diazirine)Phenylthiourea is a specialized, high-purity phospholipid derivative designed for advanced biochemical research and development. This compound is critical for applications requiring precise photoaffinity labeling and cross-linking studies due to its integrated diazirine and thiourea functional groups. It is primarily utilized by research scientists and product developers in the pharmaceutical, biotechnology, and life sciences sectors for membrane protein studies, lipidomics, and probe development.

Application

• Photoaffinity Labeling Probe: A key reagent for covalently tagging and identifying lipid-protein interaction sites in biological membranes.
• Membrane Protein Research: Used to study the structure, function, and dynamics of integral membrane proteins within lipid bilayers.
• Lipidomics and Metabolomics: Serves as a chemical standard or a derivatization agent for the analysis of complex lipid mixtures via mass spectrometry.
• Drug Discovery: Employed in target identification and validation stages to elucidate the binding mechanisms of potential therapeutic compounds.
• Bioconjugation and Probe Synthesis: Acts as a versatile building block for creating custom fluorescent or affinity-tagged lipid probes.
• Material Science: Used in the surface functionalization of nanoparticles and biomaterials for targeted delivery systems.

Basic Information

Item	Details
Product Name	N'-(1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethyl)-n-(3-(3-Trifluoromethyl)Diazirine)Phenylthiourea
CAS No.	137043-97-1
Molecular Formula	C49H81F3N4O7PS
Molecular Weight	942.22 g/mol
Synonyms	1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[3-(3-(trifluoromethyl)diazirin-3-yl)phenyl]thiourea; DMPE Photoaffinity Label; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine crosslinker; Trifluoromethylphenyl diazirine phospholipid; Photoactivatable phosphatidylethanolamine derivative; (3-(3-Trifluoromethyl)diazirin-3-yl)phenyl isothiocyanate DMPE adduct; DMPE-TPD; Lipid-based photo-crosslinker
EINECS	Contact for details

Quality Control

Every batch of N'-(1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethyl)-n-(3-(3-Trifluoromethyl)Diazirine)Phenylthiourea is manufactured under strict quality protocols to ensure the high purity and consistency required for sensitive research applications. Our quality assurance includes comprehensive analytical testing via NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under an inert atmosphere such as argon or nitrogen. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.