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S-(4-Bromo-2,3-Dioxobutyl)Glutathione CAS NO 136954-46-6
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CAS No.:136954-46-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
S-(4-Bromo-2,3-Dioxobutyl)Glutathione is a specialized, high-purity biochemical reagent designed for advanced research and development applications. This compound serves as a critical tool for studying enzyme inhibition, oxidative stress pathways, and the biochemical mechanisms of glutathione transferases. It is essential for pharmaceutical R&D teams, academic research institutions, and diagnostic kit manufacturers focused on metabolic studies and drug discovery. Our supply ensures consistent quality and reliable availability for your most demanding projects.
Application
- Biochemical Research: A key substrate and inhibitor for studying glutathione S-transferase (GST) enzymes and related metabolic pathways.
- Pharmaceutical Development: Used in the research and screening of potential therapeutic agents targeting oxidative stress and detoxification processes.
- Enzyme Kinetics Studies: Employed to investigate enzyme mechanisms, inhibition constants (Ki), and catalytic activity of GST isoforms.
- Diagnostic Reagent Synthesis: Serves as a precursor or intermediate in the development of specialized diagnostic assays and research kits.
- Metabolomics & Proteomics: A valuable tool for labeling studies and understanding post-translational modifications related to cellular redox states.
- Academic Research: Utilized in university and institutional labs for fundamental research in biochemistry, toxicology, and cell biology.
Basic Information
| Product Name | S-(4-Bromo-2,3-Dioxobutyl)Glutathione |
| CAS No. | 136954-46-6 |
| Molecular Formula | C14H21BrN3O8S |
| Molecular Weight | 463.30 g/mol |
| Synonyms | S-(4-Bromo-2,3-dioxobutyl)glutathione; 4-Bromo-2,3-dioxobutyl glutathione; GST Inhibitor; Glutathione S-(4-bromo-2,3-dioxobutyl) ester; BDG; (2S)-2-Amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-[(4-bromo-2,3-dioxobutyl)sulfanyl]ethyl]carbamoyl}butanoic acid |
| EINECS | Contact for details |
Quality Control
Every batch of S-(4-Bromo-2,3-Dioxobutyl)Glutathione is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity data, for complete traceability and compliance with research-grade standards. Our quality commitment supports reproducible results in your critical applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC/IR) | Conforms to reference standard |
| Assay (HPLC) | ≥ 95.0% |
| Purity (HPLC) | ≥ 98.0% (Area %) |
| Water Content (KF) | ≤ 2.0% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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