Description

Proangiotensin-12 (Human) is a bioactive peptide fragment that serves as a key intermediate in the renin-angiotensin system (RAS). This compound is of significant interest for research into cardiovascular physiology, hypertension, and related metabolic pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers for biochemical studies, assay development, and as a reference standard.

Application

• Biomedical Research: Fundamental studies on the renin-angiotensin system, blood pressure regulation, and cardiovascular disease mechanisms.
• Pharmaceutical Development: Screening and validation of novel drug candidates targeting angiotensin pathways for hypertension and heart failure.
• Diagnostic Reagent Production: Used as a critical component or calibrator in immunoassay kits for measuring angiotensin-related biomarkers.
• Academic & Clinical Studies: Investigating the role of angiotensin precursors in various physiological and pathological states.
• Reference Standard: Serves as a high-purity qualitative and quantitative standard for analytical method development and quality control in related bioproducts.

Basic Information

Product Name	Proangiotensin-12 (Human)
CAS No.	136865-09-3
Molecular Formula	C78H121N23O19
Molecular Weight	1644.9 g/mol
Synonyms	Angiotensin-12; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile; DRVYIHPFHLVI; Human Proangiotensin-12; A-12; RAS Precursor Peptide
EINECS	Contact for details

Quality Control

Our Proangiotensin-12 (Human) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.