Description

2,6-Dimethyl-D-Tyrosine CAS NO 136771-16-9 is a non-natural, synthetic derivative of the amino acid tyrosine, specifically engineered with methyl groups at the 2 and 6 positions of the aromatic ring and in the D-configuration. This structural modification is critical for enhancing metabolic stability and receptor selectivity, making it a valuable building block in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel peptide-based therapeutics, diagnostic agents, and biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel peptide hormones, enzyme inhibitors, and receptor-targeted drugs.
• Peptide-Based Drug Discovery: Used in solid-phase and solution-phase peptide synthesis to incorporate unique structural features that modulate bioavailability and binding affinity.
• Biochemical Research: Serves as a standard or reagent in studies investigating tyrosine metabolism, enzyme mechanisms, and structure-activity relationships (SAR).
• Diagnostic Agent Development: Employed in the design and synthesis of radiolabeled compounds (e.g., for PET imaging) targeting specific biological pathways.
• Asymmetric Synthesis: Acts as a chiral precursor or auxiliary in the preparation of complex, optically active molecules for medicinal chemistry.

Basic Information

Product Name	2,6-Dimethyl-D-Tyrosine
CAS No.	136771-16-9
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	D-2,6-Dimethyltyrosine; (R)-2-Amino-3-(2,6-dimethyl-4-hydroxyphenyl)propanoic acid; H-D-2,6-Dmt-OH; 2,6-Dimethyl-D-tyrosine; 2,6-DMT; D-2,6-Dimethyl-4-hydroxy-phenylalanine; 136771-16-9; (2R)-2-Amino-3-(2,6-dimethyl-4-hydroxyphenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our 2,6-Dimethyl-D-Tyrosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.