Description

γ-Glutamyl-Thiothreonyl-Glycine is a specialized synthetic peptide derivative of significant interest in advanced biochemical research and development. This compound serves as a critical building block and model substrate for studying enzyme kinetics, metabolic pathways, and peptide-based drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on enzymology, proteomics, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a specific substrate or inhibitor in enzymatic assays to study the activity of γ-glutamyl transpeptidase and related enzymes.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and analysis of novel peptide-based pharmaceuticals and prodrugs.
• Proteomics & Metabolomics: Employed as a tool compound for investigating glutathione metabolism and cellular redox signaling pathways.
• Academic Research: Utilized in university and institutional labs for fundamental studies on peptide bond formation, stability, and degradation mechanisms.
• Diagnostic Reagent Formulation: Acts as a component in the development of specialized diagnostic kits for enzyme activity measurements.

Basic Information

Product Name	γ-Glutamyl-Thiothreonyl-Glycine
CAS No.	136567-42-5
Molecular Formula	C13H21N3O7S
Molecular Weight	363.39 g/mol
Synonyms	L-γ-Glutamyl-L-thiothreonylglycine; γ-Glu-Thr(S)-Gly; γ-Glutamyl-Thiothreonyl-Glycine; GGT Substrate Analog; NSC 339586; Thiothreonyl Glycine γ-Glutamyl Derivative; L-Thiothreonine, N-(N-L-γ-glutamyl)glycyl-
EINECS	Contact for details

Quality Control

Our γ-Glutamyl-Thiothreonyl-Glycine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for research-grade biochemicals, ensuring reliable performance as a tool compound in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.