Description

Bq-123 Sodium Salt is a high-purity, endothelin receptor antagonist used in advanced research and development. This compound is critical for studying cardiovascular and pulmonary pathways, offering researchers a reliable tool for investigating receptor-specific mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic institutions, and biotechnology companies focused on drug discovery for hypertension and related conditions.

Application

• Pharmacological Research: As a selective endothelin A (ETA) receptor antagonist for in vitro and in vivo studies.
• Cardiovascular Disease Models: Investigation of vasoconstriction, blood pressure regulation, and heart failure pathways.
• Pulmonary Research: Study of pulmonary hypertension and related vascular remodeling processes.
• Biochemical Assay Development: Used as a reference standard in high-throughput screening and binding assays.
• Preclinical Drug Development: A key intermediate or reference compound in the development of novel therapeutic agents.

Basic Information

Product Name	Bq-123 Sodium Salt
CAS No.	136553-81-6
Molecular Formula	C34H49N7O7•xNa
Molecular Weight	Contact for details
Synonyms	BQ-123 Sodium Salt; Cyclo(-D-Trp-D-Asp-L-Pro-D-Val-L-Leu-) Sodium Salt; BQ 123; BQ123; Endothelin A Receptor Antagonist BQ-123; (3S,6R,9S,12R,18S)-9-(1H-Indol-3-ylmethyl)-18-isobutyl-3-(1-methylpropyl)-6-[(sodium oxido)oxidophosphoryl]methyl-1,4,7,10,13-pentaazacyclooctadecane-2,5,8,11,14-pentaone
EINECS	Contact for details

Quality Control

Our Bq-123 Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of research applications. A Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤5.0%
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.