Description

Cyclo(Valyl-Leucyl-Tryptophyl-Glutamyl-Alanyl) is a synthetic cyclic pentapeptide with the CAS number 136553-73-6. This compound is of significant interest in pharmaceutical research and development due to its potential as a bioactive scaffold or a precursor for more complex therapeutic agents. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in peptide chemistry, drug discovery, and biochemical studies.

Application

• Pharmaceutical Research: Serves as a key intermediate or a model compound in the development of novel peptide-based therapeutics.
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic assays to study protease activity and specificity.
• Drug Discovery: Acts as a structural template for designing and synthesizing new molecules with targeted biological activity.
• Academic Research: Employed in university and institutional labs for studying peptide synthesis, cyclization techniques, and structure-activity relationships (SAR).
• Bioconjugation: Potential use in creating peptide-drug conjugates or labeled probes for diagnostic applications.

Basic Information

Product Name	Cyclo(Valyl-Leucyl-Tryptophyl-Glutamyl-Alanyl)
CAS No.	136553-73-6
Molecular Formula	C33H46N6O7
Molecular Weight	638.76 g/mol
Synonyms	Cyclo(Val-Leu-Trp-Glu-Ala); Cyclo(V-L-W-E-A); c(VLWEA); Cyclic Pentapeptide V-L-W-E-A; Cyclo(L-Valyl-L-leucyl-L-tryptophyl-L-glutamyl-L-alanyl); L-Alanine, L-glutamyl-L-tryptophyl-L-leucyl-L-valyl-1,5-dioxo-; (3S,6S,9S,15S,18S)-3-(2-Amino-2-oxoethyl)-6-(1H-indol-3-ylmethyl)-9-(2-methylpropyl)-15-methyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,16-hexaazacyclooctadecane-18-carboxylic acid
EINECS	Contact for details

Quality Control

Our Cyclo(Valyl-Leucyl-Tryptophyl-Glutamyl-Alanyl) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.