Description

Neurokinin A (3-10), Lysyl(3)-Glycyl(8)-R-Lactam-Leucine(9)- is a synthetic peptide fragment derived from the endogenous neuropeptide Neurokinin A. This compound is of significant value as a highly specific research tool for studying tachykinin receptor pharmacology and neurokinin signaling pathways. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in neuroscience, pain research, and inflammatory disease studies.

Application

• Neuroscience Research: As a selective ligand for investigating the biological functions and distribution of Neurokinin A receptors (NK2 receptors).
• Pharmacological Assay Development: Used in competitive binding assays and functional studies to screen and characterize novel receptor antagonists or agonists.
• Signal Transduction Studies: A key reagent for elucidating intracellular pathways activated by tachykinin peptides in target cells.
• Biomarker Research: Potential use in studies exploring the role of Neurokinin A fragments in physiological and pathological conditions.
• Reference Standard: Serves as a critical purity standard for the quality control of related peptide-based pharmaceuticals or research chemicals.
• Drug Discovery Programs: Integral to structure-activity relationship (SAR) studies aimed at developing new therapeutics for conditions like asthma, irritable bowel syndrome, and chronic pain.

Basic Information

Product Name	Neurokinin A (3-10), Lysyl(3)-Glycyl(8)-R-Lactam-Leucine(9)-
CAS No.	136548-07-7
Molecular Formula	C44H71N13O11
Molecular Weight	958.1 g/mol
Synonyms	NKA(3-10), Lys(3)-Gly(8)-R-Lactam-Leu(9)-NKA(3-10); [Lys3, Gly8-lactam-Leu9]-Neurokinin A(3-10); Neurokinin A fragment 3-10 analog; Tachykinin peptide fragment; [Lys3,D-Gly8(lactam),Leu9]NKA(3-10); NK2 receptor ligand fragment; H-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2 (Neurokinin A) derivative
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and analyzed under strict quality management systems. Each batch of Neurokinin A (3-10) analog undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all relevant specifications to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.