Description

4-Trifluoromethyl-2-Methylthio-Pyrimidine CAS NO 136547-20-1 is a high-value pyrimidine derivative, a key building block in advanced organic synthesis. Its trifluoromethyl and methylthio substituents make it a versatile intermediate for creating complex molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group can improve efficacy and environmental stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Medicinal Chemistry: Employed in drug discovery programs for structure-activity relationship (SAR) studies and library synthesis.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and the production of other fine chemicals and complex heterocycles.

Basic Information

Product Name	4-Trifluoromethyl-2-Methylthio-Pyrimidine
CAS No.	136547-20-1
Molecular Formula	C6H5F3N2S
Molecular Weight	194.18 g/mol
Synonyms	2-(Methylthio)-4-(trifluoromethyl)pyrimidine; 4-(Trifluoromethyl)-2-(methylthio)pyrimidine; 2-Methylthio-4-trifluoromethylpyrimidine; Pyrimidine, 2-(methylthio)-4-(trifluoromethyl)-; 136547-20-1; 4-Trifluoromethyl-2-methylsulfanylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Trifluoromethyl-2-Methylthio-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.