Description

Pyrimidine, 4-(Trifluoromethyl)- (9Ci) is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique electronic and steric properties imparted by the trifluoromethyl group attached to the pyrimidine ring, which is crucial for modulating the biological activity and physicochemical characteristics of target molecules. This high-purity intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances metabolic stability and lipophilicity.
• Material Science Research: Serves as a building block for designing novel organic electronic materials, liquid crystals, and functional polymers.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tag in the development of chemical probes and enzyme inhibitors for biological pathway studies.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring the introduction of a fluorinated pyrimidine moiety.

Basic Information

Product Name	Pyrimidine, 4-(Trifluoromethyl)- (9Ci)
CAS No.	136547-16-5
Molecular Formula	C5H3F3N2
Molecular Weight	148.09 g/mol
Synonyms	4-(Trifluoromethyl)pyrimidine; 4-Trifluoromethylpyrimidine; α,α,α-Trifluoro-p-tolunitrile; Pyrimidine, 4-(trifluoromethyl)-; 4-CF3-Pyrimidine
EINECS	Contact for details

Quality Control

Our Pyrimidine, 4-(Trifluoromethyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.