Description

Protein Kau, Fab Fragment is a purified immunoglobulin fragment derived from a specific monoclonal antibody. This high-purity biological reagent is critical for research and development applications requiring precise antigen targeting without the effector functions of a full antibody. It is primarily utilized by biotechnology and pharmaceutical companies engaged in immunology research, diagnostic assay development, and therapeutic discovery programs.

Application

• Immunoassay Development: Used as a capture or detection reagent in ELISA, lateral flow assays, and other immunodiagnostic platforms.
• Structural Biology Studies: Employed in X-ray crystallography and cryo-electron microscopy to study antigen-antibody interactions and complex structures.
• Therapeutic Research: Serves as a key component in the development of bispecific antibodies, antibody-drug conjugates (ADCs), and other novel biologic formats.
• Cell Sorting and Isolation: Utilized in fluorescence-activated cell sorting (FACS) and magnetic-activated cell sorting (MACS) for specific cell population targeting.
• Neutralization Assays: Applied in virology and microbiology research to block specific pathogen receptors or toxins.
• Affinity Purification: Immobilized on chromatography resins for the specific purification of target antigens or proteins from complex mixtures.

Basic Information

Product Name	Protein Kau, Fab Fragment
CAS No.	136542-96-6
Molecular Formula	Contact for details
Molecular Weight	~50 kDa (Approximate, varies by glycosylation)
Synonyms	Kau Fab Fragment; Fab fragment of Anti-Kau monoclonal antibody; Immunoglobulin Fab fragment Kau; Antigen-binding fragment Kau; Monoclonal Antibody Fab Fragment (Kau); Kau mAb Fab; Fab Region (Kau); Proteolytic Fragment of Immunoglobulin G (Kau)
EINECS	Contact for details

Quality Control

Our Protein Kau, Fab Fragment is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot is subjected to a comprehensive suite of analytical tests, including purity assessment by SDS-PAGE and size-exclusion HPLC, confirmation of fragment integrity, and functional activity testing. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure containers are sealed properly after use.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Purity (SDS-PAGE, reduced)	> 95%
Purity (Size-Exclusion HPLC)	> 90% monomer
Protein Concentration	> 1.0 mg/mL (after reconstitution)
Endotoxin Level	< 1.0 EU/mg
Sterility (Membrane Filtration)	Sterile
Biological Activity (ELISA/Binding)	Retains specific antigen-binding activity

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.