Description

4-Pyrimidinecarbonylchloride,6-Chloro-2-Methyl-(9Ci) is a high-purity, reactive heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key acyl chloride intermediate, enabling the efficient introduction of the 4-pyrimidinecarbonyl moiety into target molecules. Pharmaceutical, agrochemical, and advanced material researchers need it for developing novel active ingredients and functional compounds. Its precise structure facilitates targeted molecular modifications in R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Critical for synthesizing novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for creating functional polymers and organic electronic materials.
• Chemical Biology Probes: Enables the labeling and study of biological targets through its reactive carbonyl chloride group.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical producers offering bespoke synthesis services.
• Academic & Industrial R&D: Supports fundamental research in heterocyclic and medicinal chemistry across global institutions.

Basic Information

Item	Detail
Product Name	4-Pyrimidinecarbonylchloride,6-Chloro-2-Methyl-(9Ci)
CAS No.	136518-02-0
Molecular Formula	C7H4Cl2N2O
Molecular Weight	203.03 g/mol
Synonyms	6-Chloro-2-methylpyrimidine-4-carbonyl chloride; 2-Methyl-6-chloropyrimidine-4-carbonyl chloride; 4-Pyrimidinecarbonyl chloride, 6-chloro-2-methyl-; 6-Chloro-2-methyl-4-pyrimidinecarbonyl chloride; (6-Chloro-2-methylpyrimidin-4-yl)carbonyl chloride; 6-Chloro-2-methylpyrimidine-4-carboxylic acid chloride; 4-Carboxy-6-chloro-2-methylpyrimidine chloride; 136518-02-0
EINECS	Contact for details

Quality Control

Every batch of 4-Pyrimidinecarbonylchloride,6-Chloro-2-Methyl-(9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for all shipments. Our quality commitment supports compliance in cGMP and ISO-guided environments for research and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.