Description

L-Serine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-, 2-Propenyl Ester is a protected amino acid derivative, specifically a Fmoc (9-fluorenylmethoxycarbonyl) serine derivative with an allyl ester protecting group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require high-purity, specialized intermediates for constructing bioactive peptide sequences.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the automated, sequential construction of custom peptide chains.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, hormones, and diagnostic agents.
• Bioconjugation & Protein Engineering: Serves as a precursor for introducing serine residues with orthogonal protecting groups for site-specific modifications.
• Combinatorial Chemistry Libraries: Employed to generate diverse arrays of serine-containing compounds for high-throughput screening.
• Academic & Industrial Research: A fundamental reagent for studying peptide structure, function, and synthesis methodologies.
• Production of Specialty Peptides: Used in the manufacture of therapeutic peptides, antimicrobial peptides, and cosmetic bioactive peptides.

Basic Information

Product Name	L-Serine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-, 2-Propenyl Ester
CAS No.	136497-85-3
Molecular Formula	C22H23NO5
Molecular Weight	381.42 g/mol
Synonyms	Fmoc-Ser(Alloc)-OH; Fmoc-L-serine allyl ester; Fmoc-Ser(All)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-serine 2-propenyl ester; N-Fmoc-O-allyl-L-serine; Allyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serinate; Fmoc-Ser(All); Fmoc-L-Serine O-allyl ester
EINECS	Contact for details

Quality Control

Our L-Serine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-, 2-Propenyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to relevant industry standards for fine chemical and peptide synthesis building blocks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	Contact for details
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.