Description

Parathyroid Hormone (1-34), Arg(2)- is a synthetic bioactive peptide fragment, a key analog of the endogenous hormone. This compound is critical for research and development in bone metabolism and calcium homeostasis studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotech companies focused on metabolic disorders and osteoporosis therapeutics.

Application

• Pharmaceutical Research & Development: As a reference standard and active ingredient in preclinical studies for osteoporosis and hypoparathyroidism treatments.
• Biochemical Assay Development: Used in the calibration and validation of bioassays measuring parathyroid hormone activity and receptor binding.
• Academic & Clinical Research: Investigation of calcium and phosphate regulation mechanisms in bone and kidney physiology.
• Peptide Chemistry Studies: Serves as a model compound for studying structure-activity relationships (SAR) of peptide hormones.
• Cell Culture & In Vitro Studies: Stimulation of osteoblast activity and bone formation in experimental models.

Basic Information

Product Name	Parathyroid Hormone (1-34), Arg(2)-
CAS No.	136250-66-3
Molecular Formula	C₁₈₁H₂₉₁N₅₅O₅₁S₂
Molecular Weight	4107.6 g/mol
Synonyms	PTH (1-34), Arg(2)-; [Arg²]-PTH(1-34); Teriparatide Acetate (related analog); Parathyroid Hormone Fragment 1-34, Arg²-substituted; hPTH(1-34) [Arg²]; Osteogenic peptide; RS-66271; LY333334
EINECS	Contact for details

Quality Control

Our Parathyroid Hormone (1-34), Arg(2)- is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and peptide content, MS for identity confirmation, and stringent tests for related substances and residual solvents. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at -20°C or below. This hygroscopic and easily oxidized material should be kept under an inert atmosphere (e.g., nitrogen or argon) when the container is opened and handled in a controlled, dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC/IC)	5.0% - 12.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.