Description

Rasagiline is a potent, irreversible, and selective monoamine oxidase-B (MAO-B) inhibitor. It is a critical active pharmaceutical ingredient (API) used in the treatment of Parkinson's disease, offering neuroprotective potential and symptomatic relief. This high-purity compound is essential for pharmaceutical manufacturers developing and producing finished dosage forms, such as tablets. Rasagiline CAS NO 136236-51-6 is supplied to meet the stringent quality demands of the global pharmaceutical industry.

Application

• Pharmaceutical API: Primary use as the active ingredient in anti-Parkinson's medications.
• Neurological Disorder Treatment: Formulation into tablets for managing symptoms of idiopathic Parkinson's disease.
• Neuroprotection Research: Used in preclinical and clinical research investigating its potential disease-modifying effects.
• Combination Therapies: Serves as a key component in fixed-dose combination drugs for enhanced therapeutic outcomes.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic versions of branded Rasagiline products.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories.

Basic Information

Product Name	Rasagiline
CAS No.	136236-51-6
Molecular Formula	C12H13N
Molecular Weight	171.24 g/mol
Synonyms	Rasagiline Mesylate; TVP-1012; (1R)-N-(2-Propynyl)-2,3-dihydro-1H-inden-1-amine; (R)-N-2-Propynyl-1-indanamine; Azilect (brand name); AGN 1135; R-(+)-N-Propargyl-1-aminoindan
EINECS	Contact for details

Quality Control

Our Rasagiline is manufactured under strict quality management systems to ensure it meets the highest standards for pharmaceutical use. Each batch is subjected to comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis. We provide full traceability and support regulatory submissions with comprehensive documentation. Certificates of Analysis (COA) are available upon request, confirming compliance with relevant pharmacopeial standards (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	+14.0° to +16.0° (c=1 in methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.