Description

Dermaseptin Phyllomedusa Sauvagii is a cationic antimicrobial peptide (AMP) originally isolated from the skin secretions of the waxy monkey tree frog. This compound is of significant interest for its broad-spectrum activity against bacteria, fungi, and certain enveloped viruses. It is primarily utilized in advanced research and development within the pharmaceutical and biotechnology sectors, particularly for exploring novel anti-infective agents, studying peptide-membrane interactions, and developing biomaterials with inherent antimicrobial properties.

Application

• Antimicrobial Research: Fundamental and applied research into novel mechanisms of action against drug-resistant bacterial and fungal strains.
• Drug Discovery & Development: Serving as a lead compound or template for the design and synthesis of new peptide-based therapeutic agents.
• Biomaterial Coating: Investigation into surface functionalization for medical devices (e.g., catheters, implants) to prevent biofilm formation and infections.
• Cosmeceutical R&D: Exploration of potential applications in preservative systems or active ingredients for skincare formulations targeting microbial issues.
• Biophysical Studies: Used as a model peptide in studies of lipid bilayer interactions, membrane permeabilization, and peptide structure-activity relationships (SAR).
• Veterinary Pharmaceutical Research: Potential development of antimicrobial treatments for animal health.

Basic Information

Product Name	Dermaseptin Phyllomedusa Sauvagii
CAS No.	136212-91-4
Molecular Formula	C164H273N51O44
Molecular Weight	~3619.2 g/mol
Synonyms	Dermaseptin S; Dermaseptin-S; Dermaseptin S Peptide; Phylloseptin-S; ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ; Antimicrobial Peptide Dermaseptin S; DRS-S
EINECS	Contact for details

Quality Control

Our Dermaseptin Phyllomedusa Sauvagii is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for research applications. Each lot is accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) are provided, detailing purity assessed by HPLC, molecular weight confirmation by Mass Spectrometry, and other relevant analytical data. We adhere to cGMP guidelines where applicable to support our clients' development needs.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Molecular Weight	3619.2 ± 2.0 Da (by MS)
Water Content (KF)	≤ 5.0 %
Acetate Content (HPLC)	≤ 10.0 %
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.