Description

n-Fmoc-(L-Alanine-Ul-14C) Ethanol*Solution is a radiolabeled, protected amino acid derivative supplied as a solution in ethanol for enhanced stability and handling. This compound is essential for conducting precise metabolic and pharmacokinetic tracer studies, particularly in the development of peptide-based pharmaceuticals. It is primarily utilized by research scientists and process development teams in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors.

Application

• Radiolabeled Tracer Synthesis: Critical for the synthesis of carbon-14 labeled peptides and proteins to study absorption, distribution, metabolism, and excretion (ADME).
• Pharmaceutical R&D: Used in the research and development of novel peptide therapeutics, enabling detailed metabolic pathway analysis.
• Biochemical Research: Serves as a building block in solid-phase peptide synthesis (SPPS) for creating isotopically labeled peptides for structural and functional studies.
• Metabolic Studies: Facilitates the investigation of amino acid and peptide metabolism in both in vitro and in vivo models.
• Process Chemistry: Employed in the scale-up and optimization of peptide manufacturing processes requiring radiolabeling for tracking.
• Regulatory Support Studies: Provides the labeled material necessary for conducting safety and environmental fate studies required for regulatory submissions.

Basic Information

Product Name	n-Fmoc-(L-Alanine-Ul-14C) Ethanol*Solution
CAS No.	136132-75-7
Molecular Formula	C₁₉H₁₇¹⁴CNO₄ (Unlabeled core structure)
Molecular Weight	Contact for details
Synonyms	Fmoc-Ala(14C)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine-ul-14C; Fmoc-L-alanine-ul-14C; (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)propanoic-ul-14C acid; 14C-Labeled Fmoc-L-alanine; Fmoc-14C-Ala-OH; Carbon-14 Labeled Fmoc-Alanine; Radiolabeled Fmoc Protected Alanine
EINECS	Contact for details

Quality Control

Every batch of our radiolabeled compounds is manufactured and tested under strict quality systems to ensure radiochemical purity and specific activity meet exacting research standards. Comprehensive Certificates of Analysis (COA) are provided, detailing results for identity, assay, radiochemical purity, and solvent content. Our quality commitment supports compliance with GLP and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated). Due to the highly volatile nature of the ethanol solvent and the light-sensitive properties of the compound, ensure containers are securely sealed and stored in a dedicated, well-ventilated area. For long-term storage, consider aliquoting under inert atmosphere to minimize degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95% (by UV, Fmoc chromophore)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Contact for details (mCi/mmol)
Solvent (Ethanol) Content	Specified on COA
Chemical Purity (HPLC)	≥ 98%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.