Description

Benzenemethanamine, 4-(Difluoromethoxy)-.Alpha.-Methyl- is a specialized aromatic amine derivative, distinguished by its difluoromethoxy and α-methyl substituents. This compound serves as a critical high-purity building block in advanced organic synthesis, offering unique reactivity for constructing complex molecular architectures. It is primarily required by R&D and production teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapies.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, leveraging its fluorine-containing moiety for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production and process development.

Basic Information

Product Name	Benzenemethanamine, 4-(Difluoromethoxy)-.Alpha.-Methyl-
CAS No.	136123-72-3
Molecular Formula	C9H11F2NO
Molecular Weight	187.19 g/mol
Synonyms	4-(Difluoromethoxy)-α-methylbenzenemethanamine; 1-[4-(Difluoromethoxy)phenyl]ethan-1-amine; α-Methyl-4-(difluoromethoxy)benzylamine; 4-(Difluoromethoxy)amphetamine (DFMA) derivative; 4-(Difluoromethoxy)-α-methylbenzylamine; (RS)-1-[4-(Difluoromethoxy)phenyl]ethylamine; p-(Difluoromethoxy)amphetamine intermediate
EINECS	Contact for details

Quality Control

Our production of Benzenemethanamine, 4-(Difluoromethoxy)-.Alpha.-Methyl- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthesis workflows. Each lot is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect purity and stability. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.