Description

γ-Lactam(11) Human Growth Hormone (6-13) is a synthetic peptide fragment derived from the human growth hormone (hGH) sequence, specifically incorporating a γ-lactam bridge at position 11. This compound is a critical intermediate and research tool for studying the structure-activity relationships of hGH and for the development of novel peptide-based therapeutics. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research institutions focused on endocrinology, metabolic disorders, and peptide drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis and study of human growth hormone analogs and mimetics.
• Structure-Activity Relationship (SAR) Studies: Used to investigate the biological function of specific regions of the hGH molecule by modifying the peptide backbone.
• Peptide Library Synthesis: Acts as a building block for creating focused libraries of hGH-derived peptides to screen for biological activity.
• Reference Standard: Employed as a high-purity analytical standard in quality control and method development for hGH-related peptide analysis.
• Bioconjugation & Probe Development: Utilized as a starting material for creating labeled (e.g., fluorescent, radioactive) probes for receptor binding and imaging studies.
• Academic & Clinical Research: Supports fundamental research into growth hormone physiology, signaling pathways, and potential therapeutic applications.

Basic Information

Product Name	γ-Lactam(11) Human Growth Hormone (6-13)
CAS No.	136101-07-0
Molecular Formula	C44H62N12O10
Molecular Weight	918.04 g/mol
Synonyms	hGH (6-13) γ-lactam derivative; Human Somatotropin Fragment 6-13 γ-lactam; H-Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-NH2 (Lactam bridge: Gln11-Cys14); Cyclic hGH (6-13) peptide; Growth Hormone Releasing Peptide (GHRP) analog; GHRP-6 lactam analog; CAS 136101-07-0
EINECS	Contact for details

Quality Control

Our γ-Lactam(11) Human Growth Hormone (6-13) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.