Description

Boc-n-Me-Allo-Ile-Oh is a protected, non-proteinogenic amino acid derivative widely utilized in advanced peptide synthesis. This high-purity building block is essential for introducing structural complexity and specific stereochemistry into peptide chains, enabling the development of novel bioactive compounds. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, diagnostics, and chemical biology tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of the allo-isoleucine derivative into peptide sequences.
• Pharmaceutical Research: Used in the R&D of novel peptide drugs, including antimicrobial peptides (AMPs) and hormone analogs, where stereochemical control is critical.
• Peptidomimetic Design: Serves as a scaffold for creating modified peptides with enhanced stability, bioavailability, or receptor selectivity.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged peptides for studying protein-protein interactions and enzymatic activity.
• Combinatorial Chemistry Libraries: A valuable building block for generating diverse arrays of peptide-like compounds for high-throughput screening.

Basic Information

Product Name	Boc-n-Me-Allo-Ile-Oh
CAS No.	136092-80-3
Molecular Formula	C15H29NO5
Molecular Weight	303.40 g/mol
Synonyms	tert-Butyl (2S,3S)-3-[(tert-butoxycarbonyl)(methyl)amino]-2-methylpentanoate; (2S,3S)-3-[(tert-Butoxycarbonyl)(methyl)amino]-2-methylpentanoic acid tert-butyl ester; N-Boc-N-methyl-D-allo-isoleucine tert-butyl ester; Boc-N-Me-D-allo-Ile-OtBu; Boc-N-Me-allo-Ile-OtBu; N-(tert-Butoxycarbonyl)-N-methyl-D-allo-isoleucine tert-butyl ester; N-Boc-N-methyl-allo-isoleucine tert-butyl ester
EINECS	Contact for details

Quality Control

Our Boc-n-Me-Allo-Ile-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.