Description

[Ser2]-Neuromedin C CAS NO 136058-54-3 is a synthetic peptide analog of the endogenous neuropeptide neuromedin C, also known as gastrin-releasing peptide (GRP). This compound is a critical research tool for studying the GRP receptor signaling pathway, which plays a significant role in various physiological and pathological processes. It is primarily utilized by researchers and developers in the fields of neuroscience, oncology, and gastrointestinal pharmacology for in vitro and in vivo studies.

Application

• Biomedical Research: Fundamental studies on the role of gastrin-releasing peptide (GRP) and its receptor in cellular signaling and communication.
• Cancer Research: Investigation of GRP receptor expression and function in various cancers, including prostate, lung, and pancreatic cancers, for potential therapeutic targeting.
• Neuroscience Studies: Exploration of neuromedin C's effects on the central nervous system, including its potential role in regulating feeding behavior, stress response, and memory.
• Drug Discovery & Development: Serving as a reference standard or a lead compound in the development of novel GRP receptor agonists or antagonists.
• Gastrointestinal Physiology: Research into the peptide's effects on gastric acid secretion, smooth muscle contraction, and other digestive functions.
• Receptor Binding Assays: Used as a labeled or unlabeled ligand in competitive binding studies to characterize GRP receptor affinity and density.

Basic Information

Product Name	[Ser2]-Neuromedin C
CAS No.	136058-54-3
Molecular Formula	C57H83N17O13S
Molecular Weight	1214.43 g/mol
Synonyms	Gastrin-Releasing Peptide (GRP) (7-14), Ser2-GRP(7-14); H-Ser-Leu-Ala-Val-Gly-His-Leu-Met-NH2; Neuromedin C (human, porcine, rat); GRP-7-14; L-Serine-L-leucyl-L-α-alanyl-L-valylglycyl-L-histidyl-L-leucyl-L-methioninamide
EINECS	Contact for details

Quality Control

Our [Ser2]-Neuromedin C is manufactured under strict quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Specifications can be customized to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.