Description

S-(6-Purinyl)Glutathione is a chemically modified derivative of the essential tripeptide glutathione, where a purinyl moiety is attached at the sulfur atom. This structural modification creates a valuable biochemical tool and potential precursor for research into redox biology, enzyme inhibition, and cellular signaling pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for advanced biochemical studies and as a specialized intermediate in probe development.

Application

• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies related to glutathione S-transferases and other redox-sensitive proteins.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting oxidative stress pathways.
• Probe Development: Acts as a precursor for creating fluorescent or affinity-labeled probes to study glutathione metabolism and localization within cells.
• Metabolic Studies: Employed in research to investigate the role of modified glutathione species in cellular defense mechanisms and detoxification processes.
• Reference Standard: Used as a high-purity analytical standard in method development and quality control for related pharmaceutical compounds.

Basic Information

Product Name	S-(6-Purinyl)Glutathione
CAS No.	136040-02-3
Molecular Formula	C₁₅H₂₂N₈O₆S
Molecular Weight	442.45 g/mol
Synonyms	S-(Purin-6-yl)glutathione; 6-Purinylglutathione; Glutathione, S-(6-purinyl)-; γ-Glutamylcysteinylglycine S-(6-purinyl) derivative; NSC 401005; L-γ-Glutamyl-L-cysteinylglycine S-(6-purinyl); Purinyl-glutathione conjugate
EINECS	Contact for details

Quality Control

Our S-(6-Purinyl)Glutathione is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.