Description

S-(6-Purinyl)Homocysteine is a specialized biochemical building block, a purine-modified homocysteine derivative. This compound is of significant interest in pharmaceutical research and development, particularly in the synthesis of novel nucleoside analogs and enzyme inhibitors. It serves as a critical intermediate for researchers in medicinal chemistry and biochemistry, enabling the exploration of new therapeutic pathways. Its precise structure makes it valuable for targeted studies in metabolic and epigenetic regulation.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside-based drug candidates and prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving transmethylation pathways and homocysteine metabolism.
• Medicinal Chemistry: Serves as a precursor for creating analogs to investigate structure-activity relationships (SAR) in anticancer or antiviral agent development.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical compounds.
• Life Science Reagent: Utilized in laboratory settings for studying cellular processes related to purine metabolism and one-carbon unit transfer.

Basic Information

Product Name	S-(6-Purinyl)Homocysteine
CAS No.	136040-01-2
Molecular Formula	C10H13N5O2S
Molecular Weight	267.31 g/mol
Synonyms	S-(Purin-6-yl)-L-homocysteine; 6-[(2S)-2-Amino-4-mercaptobutanoyl]-1H-purine; L-Homocysteine, S-(6-purinyl)-; Purine-6-thiohomocysteine; 6-Mercaptopurine homocysteine conjugate; NSC 339587; S-(1H-Purin-6-yl)homocysteine
EINECS	Contact for details

Quality Control

Our S-(6-Purinyl)Homocysteine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. For custom synthesis or specific purity requirements, our technical team is available for consultation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee (L-isomer)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.